TITRALGAN Tablets for pain, 10 pcs

Instructions for use for TITRALGAN Tablets for pain, 10 pcs

Detailed instructions for TITRALGAN Tablets for pain, 10 pcs

Field of use

• The preparation is a combination of acetylsalicylic acid and paracetamol, two active ingredients from the group of pain inhibitors and fever (analgesic/antipyreticity), and caffeine.
• For adults and adolescents from the age of 12 (from 43 kg) in acute light to moderately severe pain.
• Please note the information for children and young people.

Active ingredients / ingredients / ingredients

250 mg acetylsalicylic acid
50 mg caffeine
200 mg paracetamol
Corn starch auxiliary substance (+)
Stearic acid auxiliary material (+)
Talcum auxiliary material (+)
48 mg wheat thickness auxiliary material (+)
Wheat gluten auxiliary material (+)

Contradictions

• The medicine must not be taken
  • if you are allergic to acetylsalicylic acid, paracetamol, caffeine, wheat strength or one of the other components of this medicine
  • if in the past you have reacted allergic to salicylates or other non -steroidal inflammatory inhibitors (certain remedies for pain, fever or inflammation) with asthma attacks or in any other way (e.g. Narrowing of the respiratory tract, inflammation of the nasal mucosa, nettle fever, swelling of the face, eyelids or in the mouth area/throat)
  • if you earlier in connection with an application of non-steroidal inflammatory inhibitors (NSAID) gastrointestinal bleeding or a breakthrough (perforation)
  • if you suffer from gastrointestinal/duodenum ulcers (peptic ulcers) or bleeding
  • if you have repeatedly suffered from gastrointestinal/duodenum ulcers (peptic ulcers) or bleeding (at least 2 different episodes of proven ulcers or bleeding)
  • in the case of pathologically increased bleeding (hemorrhagic diathesis)
  • if you suffer from a serious impairment of the liver or kidney function
  • in the case of severe heart muscle weakness (heart failure)
  • if you take 15 mg or more methotrexate per week at the same time
  • in the last 3 months of pregnancy
  • of children and adolescents under the age of 12 or users under 43 kg

dosage

• Always take this medicine exactly according to the instruction or exactly after the agreement made with your doctor or pharmacist. Ask your doctor, dentist or pharmacist if you are not sure.
• Dosage
  • This medicine should be used in the lowest pain -controlling dose over the shortest possible period.
  • The dosage is based on the information in the following table.
  • The maximum daily dose must not be exceeded. The respective dosage interval depends on the symptoms and the maximum total daily dose. The time interval between two applications must be at least 6 hours.
  • From 43 kg. Young people aged 12 and over and adults
    • Single dose
      • 1 - 2 Tablets (corresponding to 250 - 500 mg acetylsalicylic acid, 200 - 400 mg paracetamol and 50 - 100 mg caffeine)
    • Max. Daily dose (24 hours)
      • up to 6 tablets (corresponding to 1500 mg acetylsalicylic acid, 1200 mg paracetamol and 300 mg caffeine)
  • Liver or kidney dysfunction
    • In patients with mild to moderately heavy liver or kidney dysfunction or Gilbert-Meulengracht syndrome, the dose must reduce or the dose interval Vbe obtained (patients with severe liver or kidney dysfunction see category "contraindication").
  • Older patients
    • Due to the increased risk of side effects, these patients should begin with the lowest dosage and be monitored by a doctor.
  • Children and adolescents
    • The medicine must not be used in children under the age of 12 or below 43 kg.
    • In the case of febrile illnesses, please note the note in the "Patient notice" category".

• Duration of the application
  • Do not take the medicine without a medical or dental advice for more than 3 days.
  • Please speak to your doctor, dentist or pharmacist if you have the impression that the effect of the drug is too strong or too weak.

• If you have taken a larger amount than you should
  • Dizziness and ear blades, especially in children and older patients, can be signs of serious poisoning by acetylsalicylic acid.
  • With an overdose of paracetamol, complaints generally occur within 24 hours that include nausea, vomiting, loss of appetite, pallor and abdominal pain. There can also be severe liver damage.
  • Symptoms of poisoning through caffeine (central nervous symptoms, cardiovascular reactions up to damage to the heart muscle) can also occur when large quantities are taken in a short time.
  • If you suspect an overdose with the medicine, please notify a doctor immediately. According to the severity of overdose/poisoning, this can decide on the measures necessary.

• If you have forgotten the intake
  • Do not take the double amount if you have forgotten the prior intake.

• If you have any further questions about the application of this medicine, ask your doctor, dentist or pharmacist.

Taking

• Take the tablets unscrewed with sufficient liquid (e.g. a glass of water). Do not take on an empty stomach.

Patient information

• Particular caution when taking the drug is required
  • Side effects can be reduced by using the lowest effective dose via the shortest period required for symptom control.
  • In order to prevent the risk of overdose, it should be ensured that other medicines that are used at the same time do not contain acetylsalicylic acid, no paracetamol or caffeine.
  • Simultaneous use with other non-steroidal inflammatory inhibitors (NSAID), including so-called COX-2 inhibitors (cyclooxygenase-2 inhibitors), should be avoided.
  • Please speak to your doctor or pharmacist before taking this medicine
    • if you are allergic to other inflammatory inhibitors/anti -rheumatics (certain remedies for rheumatism or inflammation) or other allergy -causing substances
    • if you suffer from allergies (e.g. with skin reactions, itching, nettle fever) or asthma, hay fever, nasal mucosal swelling (nasal polyps) or chronic respiratory diseases
    • with simultaneous treatment with anti -blood clotting medicines
    • if you have already suffered from a gastrointestinal/duodenum ulceration (peptic ulceration) or a bleeding
    • if you suffer from a limited liver or kidney function due to diseases of the kidney or liver (e.g. liver inflammation, Gilbert-Meulengracht syndrome)
    • if you are chronically alcoholic
    • if you suffer from high blood pressure and/or heart performance weakness (heart failure). Talk to your doctor or pharmacist about it before the start of treatment.
    • before operations (even with smaller interventions such as pulling a tooth): there may be increased tendency to bleed. Please inform your doctor or dentist beforehand if you have taken this medicine.
    • if you tend to be less uric acid output: by taking it a gout attack can be triggered by this medicine.
    • in the case of cardiac arrhythmias, such as sinus-untachycardia/extrasystoles (risk of reinforcement)
    • in the event of overactive thyroid (risk of caffeine side effects)
    • in the case of pathological anxiety (risk of reinforcement)
  • Your doctor will then decide whether you may only take the drug with special caution, in reduced dosage (e.g. max. 2 tablets due to the coffin content) or under medical control.
  • Do not take the drug without medical or dental advice for more than 3 days or in higher doses.
  • It belongs to a group of medicines that can affect the fertility of women. This effect is reversible after stopping the drug (reversible).
  • Unwanted effects on the gastrointestinal tract
    • The gastrointestinal tract, ulcers and breakthroughs (perforations), also with a fatal outcome, was reported during treatment with all non-steroidal inflammatory inhibitors (NSAID). They occurred with or without prior warning symptoms or serious events in the gastrointestinal tract in the prehistory at any time of therapy.
    • The risk of this is increased with increasing NSAR dose in patients with ulcers in the history, especially with the complications bleeding or breakthrough, and in older patients. These patients should begin treatment with the lowest available dose. Here, combination therapy with gastric mucosal drugs (e.g. misoprostol or proton pump inhibitor) should be considered here. This is also recommended for patients who take other medicines who increase the risk of a disease of the gastrointestinal tract.
    • If you have a history of side effects on the gastrointestinal tract, especially at older age, you should report any unusual symptoms in the abdomen (especially gastrointestinal bleeding), especially at the beginning of therapy.
    • Caution is advisable if you get medicines that can increase the risk of ulcers or bleeding, such as: B. oral corticosteroids, anti-blood clotting drugs, such as warfarin, selective serotonin-
      Reconciliation inhibitors that are used, among other things, to treat depressive moods, or platelet aggregation inhibitors, such as acetylsalicylic acid.
    • If you have gastrointestinal bleeding or ulcers during treatment, the treatment must be canceled immediately and contact with a doctor.
    • Non-steroidal inflammatory inhibitors (NSAID) should be used in patients with a gastrointestinal disease in the history (ulcerative colitis, Crohn's disease) because their condition can deteriorate.
  • Unwanted effects on the cardiovascular system
    • Medicines such as the preparation may be associated with a slightly increased risk of heart attacks ("heart attack") or strokes. These risks increase in higher doses and longer treatment. Do not exceed the recommended dose or treatment duration (maximum 3 days)!
    • If you have heart problems or a previous stroke or think that you could have a risk to these diseases (e.g. if you have high blood pressure, diabetes or high cholesterol or are smokers), you should be with your doctor or Pharmacists speak.
  • Unwanted skin reactions
    • Under the therapy with non-steroidal inflammatory inhibitors (NSAID), very rarely about serious skin reactions with redness and bladder formation, some with a fatal outcome (exfediative dermatitis, Stevens-Johnson syndrome and toxic epidermal necolysis/lyell syndrome). The highest risk of such reactions seems to exist at the beginning of therapy, since these reactions occurred in the majority of cases in the first month of treatment. At the first sign of rashes, mucous membrane defects or other signs of a hypersensitivity reaction, the drug must be discontinued and a doctor must be consulted immediately.
  • Other information
    • If painkillers are used for a long timesen of the drug may be treated. Ask your doctor for advice if you often suffer from headache despite taking the preparation!
    • When stopping abruptly, headaches and fatigue, muscle pain, nervousness and vegetative symptoms can occur after a long -dosed, non -determined use of painkillers. This deductible symptoms subside within a few days. Until then, the re -application of painkillers should be avoided and the use of the use is not carried out again without medical advice.
    • The habitual intake of pain relievers, especially when combining several pain relieving active ingredients, can lead to permanent kidney damage with the risk of kidney failure (analgesics-nephropathy).
    • The more frequent application should also be avoided in diabetes mellitus (diabetes), alcoholism, rheumatic therapy, dehydration (heavy drying out of the body e.g. after diarrhea, high outside temperatures, excessive physical stress with strong sweating), chronically too low blood pressure, serious injuries.
    • Due to the fever -lowering effect, an improvement in the disease can be faked. If necessary, medical advice must be obtained.
  • Children and adolescents
    • The medicine must not be used in children and adolescents under the age of 12 (under 43 kg).
    • In children and adolescents over the age of 12, the preparation should only be applied to medical instructions with feverish illnesses and only if other measures do not work. If these diseases occur with long vomiting, this can be a sign of Reye syndrome, a very rare but life-threatening illness, which requires absolutely immediate medical treatment.
  • Older people
    • In older patients, side effects occur more frequently after using non-steroidal inflammatory inhibitors (NSAID), in particular bleeding and breakthroughs in the stomach and intestinal area, which may be life-threatening. Therefore, particularly careful medical monitoring is required in older patients.

• Wateriness and operating machines
  • The medicine has no or a negligible influence on the traffic and operating machines. Nevertheless, caution is always required after taking a pain reliever.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before taking this drug.
• Pregnancy
  • The preparation should not be taken during pregnancy, since pregnancy and/or the development of the unborn child can be affected. You should therefore only take the medicine in the first and second thirds of pregnancy after consultation with your doctor and after strict weighing up the benefit risk ratio. In the last third of pregnancy, you must not take the preparation due to an increased risk of complications for mother and child.
• Breastfeeding
  • The active ingredients pass into breast milk. Since adverse consequences from paracetamol and acetylsalicylic acid for the infant have not yet become known, an interruption of breastfeeding is generally not necessary if the recommended dose is used. The condition and behavior of the infant can be affected by caffeine recorded with breast milk. If you use or take higher doses for a long time, you should stop.
• Reproductive ability
  • The preparation belongs to a group of drugs that can affect the fertility of women. This effect is reversible after stopping the drug (reversible).

Hints

Miscellaneous

- The habitual taking of painkillers is dangerous. It can lead to irreparable damage to health. In general, the long-term taking of painkillers, especially when combining several pain relieving active ingredients, can lead to permanent kidney damage with the risk of kidney failure (analgesics-nephropathy).
- The long -term use of the combination of the active substance can lead to an increased risk of disease for damage damage caused by pain relievers if the kidney damage or genetic assessment is pre -existing.
- In the case of long -dosed, non -determined use of pain relievers, headaches and tiredness, muscle pain, nervousness and vegetative symptoms can occur. This sounds within a few days. Until then, painkillers will be reinforced and re -taking it again should take place without medical advice.
- When taking surgical interventions, the doctor/dentist must be questioned or informed.
- If the black chair (TEERSUFL) occurs, the doctor must be notified immediately.

- If the recommended dosage is exceeded, the liver values (transaminases) can increase. Therefore, regular control of the transaminases, especially in children, is required.