PASCORBIN Injection solution injection bottle, 20x50 ml

Instructions for use for PASCORBIN Injection solution injection bottle, 20x50 ml

Detailed instructions for PASCORBIN Injection solution injection bottle, 20x50 ml

Field of use

• Ascorbic acid (vitamin C) is a water -soluble vitamin.
• The medicine is used
  • for the therapy of clinical vitamin C deficiency states that cannot be remedied or orally substituted in diet.
  • Methemoglobinemia in childhood.

Active ingredients / ingredients / ingredients

7.5 g Ascorbic acid
Sodium hydrogen carbonate auxiliary material (+)
Water, for injection purposes auxiliary material (+)

Contradictions

• The medicine must not be used at:
  • In the following it is described when this medicine may only be used under certain conditions and only with special caution. Please ask your doctor. This also applies if this information has been on your own.
  • The preparation may only be used after consultation with your doctor in kidney stones from oxalate and certain diseases in which too much iron is stored in the body (thalassemia, hemochromatosis, sideroblastic anemia).

dosage

• Always apply the medicine exactly according to the instruction. Please ask your doctor or pharmacist if you are not quite sure.
• The medicine is generally used by a doctor.
• Unless otherwise prescribed by the doctor, the usual dose is:
  • Unless otherwise prescribed, 5 ml slowly injecting 5 ml daily, up to 50 ml injection solution as an addition to the infusion.
  • In order to prevent a vitamin C deficiency in the case of longer artificial (parenteral) nutrition, adults receive 100 to 500 mg of ascorbic acid per day (corresponding to 0.7 ml to 3.3 ml).
  • Children intravenously 5 to 7 mg ascorbic acid/kg kg per day.
  • Methemoglobinemia in childhood:
    • 500 To 1000 mg of ascorbic acid (corresponding to 3.3 ml to 6.6 ml) are intravenously injected.
    • If necessary, the gift must be repeated with the same dosage.
    • A dose of 100 mg/kg kg per day should not be exceeded.

 

• Duration of the application
  • Your doctor decides on the duration of the application due to the course of the disease and the blood values.

 

• If you have used a larger amount than you should
  • The application is interrupted. Other measures are generally not necessary, except for hemolysen or kidney stones.
  • In the event of pain in the kidney area or difficult urination after a high dose, a doctor must be informed immediately.

Taking

• The medicine is slowly injected by your doctor or other medical staff (into the veins).

Patient information

• Warnings and Precautions:
  • Injection of high doses can lead to acute kidney failure due to kidney stones by precipitation calcium oxalate crystals in the kidney. This has already been observed in doses of 1.5 - 2.5 g. Patients with an existing restriction of kidney function (renal failure) are particularly at risk for this.
  • Adequate fluid intake (approx. 1½ to 2 l per day) should be taken into account.
  • In patients with recurring kidney stone formation, the daily vitamin C dose should do not exceed 100 to 200 mg. Patients with high -grade or terminal renal failure (dialysis patients) should not receive more than 50 to 100 mg every day.
  • In patients with erythrocytic glucose-6-phosphate dehydrogenase deficiency (hereditary disturbance of the metabolism of the red blood cells), with high doses of vitamin C (more than 4 g daily), e.g. T. heavy hemolysen (resolution of red blood cells) observed. Exceeding the dosage of 100 - 500 mg ascorbic acid daily must therefore be avoided.
  • In patients with known breathing difficulties (especially by restricting breathing function, such as asthma, chronic bronchitis or smoking cough), treatment with high doses (from 7.5 g) can occur in individual cases. It is therefore recommended to start treatment with lower doses in these patients.
  • This preparation must not be mixed with drugs, the effect of which is reduced by chemical reduction.
  • Children
    • In children under the age of 12, an IV - 7 mg ascorbic acid/kg kg per day should not be exceeded in children under the age of 12.
    • As part of the therapy of methemoglobinemia in childhood, a lot of 100 mg ascorbic acid/kg kg should not be exceeded every day.
  • Older people
    • Adequate fluid intake (approx. 1½ to 2 l per day) should be taken into account.
  • Special note for diabetics
    • After parenteral administration of ascorbic acid, the detection reaction of glucose is disturbed in the blood.
  • Hints
    • According to the gift of grammar, the ascorbic acid concentration in the urine can rise to such a way that the measurement of various clinical-chemical parameters (glucose, uric acid, creatinine, inorganic phosphate) is disturbed and falsified.

 

• Wateriness and operating machines
  • There are no special precautions required.

Pregnancy

• Pregnancy
  • In pregnancy, a lot of 100 to 500 mg of ascorbic acid should not be exceeded every day.
• Breastfeeding
  • During breastfeeding, a lot of 100 to 500 mg ascorbic acid should not be exceeded every day.

Hints

Manufacturer:  Pascoe Pharmaceutical preparations, Schiffenberger Weg 55, 35394 Gießen