LOPHAKOMP B 12 Depot 1000 μg solution for injection, 100X2 ml

Composition
Lophakomp® B12 depot (1000 µg)
1 Ampoule with 2 ml solution for injection contains:
1044 µg hydroxocobalamin acetate equivalent to 1000 µg hydroxocobalamin
Other ingredients: sodium chloride, acetic acid 10%, water for injections

Cyanocobalamin and hydroxocobalamin acetate belong to the group of substances collectively referred to as “vitamin B12”. Hydroxocobalamin acetate represents a physiological depot form of vitamin B12. Both Lophakomp®-B12 injection solutions are free of preservatives.

Application areas
Vitamin B12 deficiency that cannot be corrected with nutrition. Vitamin B12 deficiency can manifest itself in the following clinical pictures:

Hyperchromic macrocytic megaloblastic anemia (pernicious anemia, Biermer anemia, Addison's anemia)
Funicular Spinal Disease

A vitamin B12 deficiency confirmed by laboratory diagnostics can occur with:
Years of malnutrition (e.g. through a strict vegetarian diet)
Malabsorption
insufficient production of intrinsic factor
Diseases in the end section of the ileum, e.g. sprue,
Fish tapeworm infestation or
Blind loop syndrome
Congenital vitamin B12 transport disorders

Instruction of dosage and kind of usage
Lophakomp® B12 depot (1000 µg):
1 Ampoule weekly (equivalent to 1000 µg hydroxocobalamin).

Lophakomp®-B12 (3000 µg) and Lophakomp®-B12-Depot (1000 µg) are usually administered intramuscularly. However, they can also be given slowly intravenously or subcutaneously. If well tolerated, the duration of use is not limited. If there is a proven vitamin B12 absorption disorder in the intestine, vitamin B12 is usually substituted for life.