Pasconeural Injectopas 2% 2 ml Injection Solution, 10 pcs

Instructions for use for Pasconeural Injectopas 2% 2 ml Injection Solution, 10 pcs

Important notes (compulsory information):

Pasco Neural® Injectopas 2% 2 ml. Active substance: Procainhydrochloride. Applications: Used in the context of neural therapeutic application principles.

For risks and side effects, read the package leaflet and ask your doctor or pharmacist.


LEAFLET: INFORMATION FOR THE USER

Pasco Neural® Injectopas 2% 2 ml
Active substance: Procainhydrochloride 20 mg per ml
Injection solution for use in adults and adolescents 15 years

Read the entire leaflet carefully before starting using this medicine, because it contains important information for you. Always use this medicine as described in the leaflet or exactly as your doctor's or pharmacist instructions.

• Lift the package leaflet. You might want to read it again.
• Ask your pharmacist if you need more information or advice.
• If you notice side effects, contact your doctor or pharmacist. This also applies to side effects that are not indicated in the leaflet. See section 4.
• If your complaints worse or no improvement occurs, you must definitely visit a doctor.

What is in this leaflet:

1. What is Pasconeural Injectopas® 2% 2 ml and what is it used for?
2. What should you be used before using Pasconeural Injectopas® 2% 2 ml Note!
3. How to apply Pasconeural Injektopas® 2% 2 ml?
4. WHAT SIDE EFFECTS ARE POSSIBLE?
5. How to keep Pasconeural Injektopas® 2% 2 ml?
6. Content of the pack and more information

1. What is Pasconeural Injectopas® 2% 2 ml and what is it used for?

Pasconeural Injektopas® 2% 2 ml is a medicine for local anesthesia (local anesthetics of ester type). Pasconeural Injectopas® 2% 2 ml is used in the context of neural therapeutic application principles.

2. What should you be 2% before using Pasconeural® Injectopas Note 2 ml?

Pasconeural Injectopas® 2% 2 ml must not be used:

• if you are hypersensitive (allergic) to procain, ester type local anesthetics, sulfonamides (certain group of antibiotics), benzoic acid (parabenses) or any other ingredients of Pasconeural Injectopas® 2% 2 ml
• with known lack of a specific body's own substance (Pseudocholine esterase) with the sequence of a significantly slowing down degradation of procain
• for injection in strikers (arteries), into the environment of the outer shell of the central nervous system (epidural) or in the spinal channel (spinal).

Warnings and Precautions:
if you are at one

• certain form of muscle weakness (myasthenia gravis)
• Disruption of the heart irritation system
• Heart muscle weakness or
• the injection should be made in an inflamed area.

Prior to the use of Pasconeural Injectopas®, the use of Pasconeural Injektopas® 2% 2 ml is generally paying attention to a good filling of the circulation, make a careful circulation monitoring and have all measures to ventilate, therapy of convulsive accidents and revival. Furthermore, the doctor must see from you whether you have an allergic reaction to other drugs that are chemically used with procain, as it can also come to an allergic reaction to procain (paragraph allergy). This can be z. B. its sulfonamides (certain group of antibiotics), oral antidiabetics (medium in diabetes), certain dyes, X-ray film winder or other means of local anesthesia,

Pasconeural Injectopas® 2% 2 ml contains sodium:
PASCONEURAL INJECTOPAS® 2% 2 ml contains sodium, but less than 1 mmol (23 mg) sodium per 2 ml, i., it is almost "Sodium free"

3. How to apply Pasconeural Injectopas® 2% 2 ml?

Always use Pasconeural Injectopas® 2% 2 ml exactly as directed in this leaflet, please ask your doctor or pharmacist if you are not sure. Pasconeural Injectopas' 2% 2 ml is generally applied by a doctor. Please ask your doctor if you are not quite clear about the application. Basically, only the smallest dose may be administered with which the desired sufficient nerve block is achieved. The dosage must be made individually according to the peculiarities of the individual case.

Unless otherwise applied by the doctor:
Adults and adolescents from 15 years with an average body size: Skinquaddling: per quaddle up to 10 Mg corresponding to 0.5 ml of pasconeural injectopas' ^ 2% 2 ml. The recommended maximum dose at snot application in tissues from which a fast recording of medicines is made is 500 Mg Procaine (corresponding to 25 ml of pasconeural injectopas' 2% 2 ml). When used in the head, neck and genital area, the recommended one-to-date maximum dose is 200 mg procainer (within 2 Hours . In patients with certain pre-existing conditions (Vascular closures, vascular associations and constrictions (Arteriosclerosis) or nerve damage in diabetes) is also the dose to reduce one third. With restricted liver or renal function, increased plasma levels can occur, especially when used repeated application. In these cases, a lower dose range is also recommended.

Please talk to your doctor if you have the impression that the effect of Pasconeural LNJetsOpas® 2% 2 ml is too strong or too weak.

Type of application:
Pasconeural Injectopas® 2% 2 ml is in the skin (intracutaneous) Injected.
Pasconeural Injectopas® 2% 2 ml Sollie only injected by persons with appropriate knowledge to successfully implement the respective application. Basically, in the case of continuous use, only low concentrated solutions are applied by procain. A repeated application of this medicine may result in reversible efficiencies due to tachyphylaxis (rapid tolerance development over the medicament). The injection solution is intended for single removal only. The application must be done immediately after opening the container. Unused remains are to be discarded.

Duration of application:
The duration of the application is not limited in principle, but observe the information under application areas. If you have used a larger amount of Pasconeural Injektopas® 2% 2 ml than you should, must be informed immediately of the attending physician.
a) Symptoms of overdose: Pasconeural Injectopas® 2% 2 ml acts in low damaging dosages as stimulants at the central nervous system, in contrast to high damaging dose areas. The Procainhydrochloride poisoning runs in 2 Phases: They become restless, complain about dizziness, acoustic and visual disturbances as well as tingling, especially on tongue and lip area. The language is washed out, chills and muscle souvenirs are harbing of a threatening spasm of convulsions concerning the whole body, in progressing poisoning of the central nervous system, it comes to an increasing malfunction of the brain stem with the symptoms of breath restraint and coma to death.
b) Emergency measures and antidote are immediately initiated by the attending physician according to the disease signs.

If you forget the application of Pasconeural® Injectopas® 2% 2 ml:
Do not apply twice the dose if you forget the previous application.

If you cancel the application of Pasconeural® Injectopas 2% 2 ml:
Treatment with Pasconeural® Injectopas0 2% 2 ml can be aborted at any time.

4. Which side effects are Möglch?

Like all medicines, Pasconeural Injektopas® can have 2% 2 ml side effects, but they do not have to occur each other. The frequency information on side effects is based on the following categories: Possible side effects: Whon They are affected by one of the subsequent side effects, do not apply Pasconeural Injectopas® 2% 2 ml and look for your doctor as soon as possible. If Procain can only be extremely slowly dismantled with them, because a particular body substance is not as active (Pseudocholine esterase deficiency), side effects can occur due to procain. When used in the neck-head area, there is a higher risk of hazards because the risk of poisoning phenomena in the central nervous system is increased.

To avoid side effects, the following points should be considered:

• In certain cases, before using Pasconeural Injectopas® 2% 2 ml additionally create a drip.
• Dosing as low as possible.
• Usually do not use a vascular additive (s. Dosage instructions).
• Before injection, carefully sucked into two levels (rotation of the cannula).
• Caution for injection in infected areas (inherent recording in reduced efficacy),
• Put injection slowly.
• Check blood pressure, pulse and pupil width.

It should be noted that under treatment with bluf kneading inhibitors (Anticoagulants, e.g. heparin), nonsteroidal anti-rheumatics or plasma replacement materials, not only an accidental vascular injury can lead to serious bleeding in the context of pain treatment, but that generally has increased bleeding tendency. Therefore, carry out corresponding laboratory tests before the use of Pasconeural Injectopas' 2% 2 ml. If necessary, the coagulation-resistant treatment must be dropped early enough. An application with simultaneous pension therapy to avoid thrombosis with low molecular weight heparin should only be carried out with special care.

Children:
For use in children and adolescents under the age of 15, there are no application experiences from which general dosage recommendations can be derived.

Old people:
In the case of older people, a dosepassuna is recommended according to the respective general condition. Application of Pasconeural Injectopas 2% 2 ml together with other medicines: Please inform your doctor or apcheker if you take / use other medicines or recently taken, even if it is non-prescription medicines. The following interactions of ProCain with other medicines are known; Extension of the effects of certain means of solving skeletal musculature (non-polarizing muscle relays)

• Reinforcement of the effect by Physostigmin (means for stimulating a part of the vegetative nervous system)
• Reduction of effectiveness of certain antibiotics (Sulfonamide).

Procain should not work together with certain resources to stimulate a part of the vegetative nervous system (Choline esterase inhibitors) are used. Among other things, the influence on procain degradation leads to an increase in the toxicity of procain. By adding small atropin quantities, an extension of the pain-switching effect is possible. Physostigmin (S.O.) can have a preventive effect against toxic procain effects in low doses.

Main chemical incompatibilities:
Procain should not be mixed with other medicines as a change in pH or electrostic cyf concentration can lead to the precipitation of the active ingredient.

Application of Pasconeural Injectopas® 2% 2 ml together with food and beverages:
No mutual impairment to be expected, as it is a solution for injection, i.e., bypassing the gastrointestinal tract is applied.

Pregnancy and breast feeding period:
Pregnancy:
Let Pasconeural Injectopas1 2% 2 ml in pregnancy only apply if your doctor is necessarily required.

Latving:
Procainhydrochloride passes into breast milk. In case of short-term use, however, interruption of breastfeeding will not be required. Is a repeated treatment or a treatment with higher doses required, you should desele.

Driving and ability to operate machines:
From your doctor, you decide on a case-by-case basis whether you are able to actively participate in road traffic, operate machines or work without a secure hold.

Unwanted, the effects of procain relating to the whole body concern especially dos central nervous and cardiovascular system, in plasma concentrations, as they are generally achieved in the case of a rule-right application, the blood pressure is usually only slightly due to the cardiac power and impact speed promoting effect of pasconeural Injectopas® 2% 2 ml influences. Procain can trigger changes in excitement propagation in the heart, which show in the ECG (as a flattened T-wave or shortened pcs -Like). A blood pressure drop can be a first sign for a relative overdose in the sense of a heart-damaging effect. As central nervous disturbances, disproportions can be triggered around the mouth, restlessness, awareness or elasticity (see also "If you have applied a larger amount of Pasconeural Injektopas® 2% 2 ml...").

Allergic reactions to Pasconeural Injektopas® 2% 2 ml in the form of nettle rash, swelling of the tissue by water inlaying ring, scraping of the respiratory tract or respiratory distraction and circulatory reactions have been described. Oriental allergies and allergy-like reactions in the form of skin inflammation with skin extraction, itching up to blistering can occur when contact with ester local anesthetics such as Pasconeural Injectopas® 2% 2 ml. In addition, as local reactions in application under the skin (subcutaneous) and muscle (intramuscular) Swells, skin drilling and bruising occur.

Message of side effects:
If you notice side effects, contact 5! E to your doctor or pharmacist. This also applies to side effects that are not indicated in this pc. You can also disclose side effects directly via the Federal Institute for Medicines and Medical Devices. Pharmacovigilance, Kurt-Georg-Kiesinger Allee 3, D-53175 Bonn, Website: View http://www.bfarm.de. By reporting side effects, do not help you to provide more information about the safety of this medicine.

5. How to keep Pasconeural Injektopas® 2% 2 ml?

Keep this medicine inaccessible to children. You may not use the drug after the expirable date specified on the container and outer wrapping according to "usable to" or "to". The expiry date refers to the last day of the month.

Storage conditions:
Do not store more than 25 ° C.

Note on durability after breaking or preparation:
The injection solution is intended for single removal only. The application must be done immediately after opening the container. Unused remains are to be discarded.

6. Content of the pack and further information

What Pasconeural Injectopas® 2% 2 ml contains:
The active ingredient is: Procainhydrochloride. 1 ml injection solution contains 20 mg of process hydrochloride.

The other ingredients are:
Sodium chloride, citric acid monohydrate, sodium hydroxide, water for injection purposes.

Like Pasconeural Injektopas® 2% 2 ml looks and content of the pack: the brown laspoules contain a clear solution. Pasconeural Injectopas® 2% 2 ml is packed with 10 ampoules 2 ml as well as clinic packs with 100 ampoules and 1,000 ampoules to 2 ML injection solution available. Not all pack sizes may be placed on the market.

Pharmaceutical entrepreneur and manufacturer:
PASCOE pharmazeutische Präparate GmbH
Shipberger way 55
D-35394 Passenger or large recipient postal code D-35383 casting
Tel.: +49 (0) 641 / 7960-0
Fax: +49 (0) 641/7960-109
E-Mail: [email protected]

This leaflet was last revised in January 2015.

Source: Information of the leaflet
Status: 03/2016