PANGROL 20,000 gastric -resistant tablets, 200 pcs

Instructions for use for PANGROL 20,000 gastric -resistant tablets, 200 pcs

Application notes

All ages

1-2 Tablets

3-5 times a day

for the meal

Application areas

Mode of action

How does the ingredient of the medicine work?

The medicine consists of digestive enzymes that are obtained from the pancreas of pigs. These are very similar to the naturally occurring digestive enzymes in the human gastrointestinal tract and mingle with the cheeky porridge after taking the stomach and intestine. There you help to crush the food by splitting the fats, proteins and carbohydrates into smaller units. In this way, the digestion of the food is supported. These are then absorbed into the blood or lymph and distributed via these transport routes into the cells of the individual tissues.

Composition

Contradictions

What speaks against an application?

Always:
- Hypersensitivity to the ingredients

Under certain circumstances - speak to your doctor or pharmacist:
- Inflammation of the pancreas, in acute condition

What about pregnancy and lactation?
- Pregnancy: According to current knowledge, the drug has no harmful effects on the development of your child or birth.
- Breastfeeding: According to current knowledge, there is no evidence that the medicine must not be applied during breastfeeding.

If the medicine has been prescribed to you despite a counter -notification, speak to your doctor or pharmacist. The therapeutic benefit can be higher than the risk of using the application.

Side effects

What adverse effects may occur?

For the medicine, only side effects are described that have so far only occurred in exceptional cases.

If you notice a disorder or change during treatment, contact your doctor or pharmacist.

For information at this point, side effects are taken into account that occurs in at least one of 1,000 patients treated.

Hints

What should you consider?
- Beware of allergy to pig protein!
- Beware of allergy to binders (e.g. carboxymethylcell cellulose with the E 466)!
- Beware of an intolerance to lactose. If you have to adhere to a diabetes diet, you should take the sugar content into account.

Detailed instructions for PANGROL 20,000 gastric -resistant tablets, 200 pcs

Field of use

• This preparation is a drug that contains digestive substances (enzymes) from the pancreas of pigs (pancreatic powder, also called pancreatin).
• It is used to treat digestive disorders caused by a reduced or lack of function of the pancreas.

Active ingredients / ingredients / ingredients

191.11 mg pankreas powder (from pig)
20,000 Phur-e triacylglycerollipase
Amylase
Proteas
Carmellosis, sodium salt auxiliary material (+)
Cellulose, microcrystalline auxiliary material (+)
Crospovidon auxiliary material (+)
Eudragit L 30 D-55 Hedge substance (+)
Hypromellic auxiliary substance (+)
133.34 mg lactose 1-water auxiliary material (+)
Macrogol 6000 Hedge Terms (+)
Magnesium stair (Ph. EUR.) [pflanzlich] Hedge material (+)
Sodium hydroxide auxiliary substance (+)
Polysorbate 80 HILDVERSTOFT (+)
Silicium dioxide, high disperser auxiliary substance (+)
Simeticon emulsion 30% auxiliary material (+)
Talcum auxiliary material (+)
Titan dioxide HILDBOFT (+)
Triethyl citrat auxiliary substance (+)
1 mmol total sodium ion hedge material (+)
Total sodium ion helper (+)
Bergamot Aroma Hedge substance (+)
Vanilla aroma hedge material (+)

Contradictions

• The medicine must not be taken,
  • if you are allergic to pancreatic powder, pork or other components of this medicine
  • if you suffer from acute inflammation of the pancreas or have an acute thrust of chronic inflammation of the pancreas during the fully pronounced phase of disease. In the subscriptions during the dietary structure (protective food), however, the administration of the preparation is sometimes useful for existing digestive disorders.

dosage

• Always take this medicine exactly after consultation with your doctor. Ask your doctor or pharmacist if you are not sure.
• Dosage
  • The recommended dose is:
    • 1- 2 Tablets per meal (corresponding to 20,000 to 40,000 pH units Lipase per meal).
    • The dosage depends on the severity of the digestive disorder, so the necessary dose can also be above it. An increase in the dose should only be carried out under medical control and aimed at improving the disease signs (e.g. fat chairs, abdominal pain). A daily enzyme dose of 15,000 to 20,000 units lipase per kilogram of body weight should not be exceeded.
    • Especially in patients with cystic fibrosis, the enzyme dose should not be higher than necessary for an appropriate fat recording .
    • The doctor should decide on the dosage in children.

 

• Duration of the application
  • The duration of the application is not subject to any limitation. It depends on the course of the disease and is determined by the doctor. If you don't feel better or worse, contact your doctor.
  • Please speak You with your doctor or pharmacist if you have the impression that the effect of the drug is too strong or too weak.

 

• If you have taken a larger amount than you should
  • Drink a lot of water and speak to your doctor or pharmacist.
  • Repeated high doses of pancreatic powder can cause scarring or thickening of the intestinal wall, which can lead to a constipation of the intestine, a disease that is called fibrosing colonopathy.
  • Extremely high doses of pancreatic powder can lead to an increase in uric acid in the blood (hyperuricaemia) and urine (hyperuricauria), especially in cystic fibrosis patients.

 

• If you have forgotten the intake
  • Do not take the double amount if you have forgotten the prior intake, but please continue with the treatment as recommended.

 

• If you cancel the intake
  • If you end or interrupt the treatment prematurely, you have to expect your symptoms to return. Take consulting with your doctor.

 

• If you have any further questions about the application of the drug, please contact your doctor or pharmacist.

Taking

• Take the medicinal product with plenty of liquid, preferably in the middle of the meal.
• Please make sure that the tablets are swallowed, as the medicine loses effect when melted and the enzymes it contains can damage the mucous membrane when it is cleared in the oral cavity. You should drink plenty of liquid (water or juice).

Patient information

• Warnings and Precautions
  • Please speak to your doctor or pharmacist before taking the preparation.
    • In patients with cystic fibrosis, a rare bowel disease called "fibrosing colo-nopathy", in which their intestine is narrowed, was reported when taking high-dose pancreatic powder products. Inform your doctor if you suffer from cystic fibrosis and take more than 10,000 pH units lipase per kilogram of body weight per day. Unusual abdominal complaints or changes in abdominal symptoms should be examined as a precaution.
    • When an allergic reaction occurs, end your treatment and speak to your doctor. An allergic reaction could contain itching, hives or rash. In some cases, a serious allergic reaction can occur, e.g. with severe skin reactions, swelling, warmth, dizziness and fainting, breathing difficulties, heartbeat. These are symptoms of a severe, possibly life -threatening state that is referred to as the "anaphylactic shock". If this is the case, you will immediately call medical help.
    • This medicine contains active enzymes that can cause mucosal damage (e.g. wounds in the oral mucosa) when the oral cavity is released. Therefore, be careful to take the preparation un -chewed.

 

• Wateriness and ability to operate machines
  • The medicine has no or a negligible influence on the roadworthiness and the ability to use machines.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before using all medicines.
• There is no sufficient experience with the application of the drug in pregnant women. There are insufficient data from animal experimental studies in relation to pregnancy, development of the unborn child, childbirth and development of the child after birth. The possible risk for humans is not known. If you are pregnant or if you breastfeed, you should not take the preparation unless your treating doctor considers taking it absolutely necessary.

Hints

Miscellaneous

It is important to be careful to swallow the preparation unz -chew, as it contains active enzymes that are released in the oral cavity, e.g. B. chewing, can lead to mucosal damage (ulcerations of the oral mucosa).

The absorption of folic acid (absorption of folic acid in the blood) can be reduced by taking pancreatic powder-containing finished medicinal products so that additional folic acid intake may be required.

The effect of the blood sugar -lowering active ingredients (oral antidiabetics) acarbosis and Miglitol can be reduced by simultaneously taking the preparation.

In individual cases, allergic reactions from the immediate type (such as rash, sneezing, tear flow, bronchospasm) and allergic reactions of the digestive tract have been described after taking pancreatic powder. If this allergic reaction occurs, the preparation must be discontinued immediately and a doctor must be consulted as soon as possible.

In patients with a characteristic malfunction of the pancreas (cystic fibrosis), the formation of narrowing (strictures) in lower intestinal sections (ileozökal region and colon ascendics) has been described in individual cases.

With the symptoms -like symptoms.
Colon lock is a known complication in patients with cystic fibrosis. If there is a symptoms -like symptoms, the possibility of intestinal narrowing should also be considered.

In patients with cystic fibrosis, an increased uric acid excretion in urine can occur, especially with the intake of high doses of pancreatin. Therefore, uric acid excretion in these patients should be checked in the urine to avoid the formation of uric acid stones.

The preparation should not be taken during the pancreatitis acute and an acute thrust of chronic pancreatitis during the florid phase of illness.

Manufacturer:  BERLIN-CHEMIE AG, Glienicker Weg 125, 12489 Berlin