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-6% L-CARN drinking solution, 50x10 ml

L-CARN drinking solution, 50x10 ml

L-CARN Trinklösung

Manufacturers: Alfasigma S.p.A.

PZN: 08796719

Dosage: Lösung

Content: 50X10 ml

Reward Points: 933

Availability: Out of stock

$119.59

$112.38

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-6% L-CARN drinking solution, 50x10 ml

Instructions for use for L-CARN drinking solution, 50x10 ml



Active ingredient: levocarnitine


Field of use

  • The preparation is used for the therapy of carnitine deficiency diseases (levocarnitine substitution therapy).
  • The medicine is used:
    • to compensate for levocarnitine losses due to defects of the so-called carnitine transporter in the cell membrane (substitution with primary systemic carnitine lack).
    • to compensate for levocarnitine losses, which can be caused by various diseases and as a side effects of certain types of treatment (substitution in the case of secondary systemic carnitin deficiency).
    • to compensate for treatment-related levocarnitine losses, which can result as a result of continuous treatment by blood linen in patients with kidney failure (substitution of dialysis-related levocarnitine losses in chronic hemodialysis, i.e. as a result of a secondary levocarnitine lack))
    • as a treatment attempt in special forms of muscle vicinity with accompanying muscle fat, which are caused by a levocarnitine deficiency of the muscles (muscular dystrophy with lipid accumulation based on a primary muscular levocarnitine deficiency).

Active ingredients / ingredients / ingredients

1 g levocarnitine
Ventracic acid auxiliary substances (+)
Saccharin sodium 2-water Hedge substance (+)
Salic acid, concentrated auxiliary material (+)
Water, cleaned auxiliary material (+)
Sodium benzoat auxiliary substance (+)

Contradictions

  • The medicine must not be taken
    • if you are hypersensitive (allergic) against the active ingredient levocarnitine or another of the other components of the preparation.

dosage

  • Always take the medicine exactly according to the instruction. Please ask your doctor or pharmacist if you are not quite sure.
  • Unless otherwise prescribed by the doctor, the usual dose is:
    • In adults
      • Single dose:
      • Total dose:
    • In children's daily dose, one or more details are distributed; 25 to 100 mg levocarnitine/kg body weight
      • with a body weight up to 5 kg
        • Single dose: max. 1/2 bottles
        • Total dose: Max. 1/2 vials, (corresponding to 500 mg levocarnitine)
      • with a body weight up to 10 kg
        • Single dose: ½ bottle
        • Total dose: max. 2 x 1/2 vials, (corresponding to 1000 mg levocarnitine)
      • with a body weight up to 15 kg
        • Single dose: 1/2 vials
        • Total dose: max. 3 x 1/2 vials, (corresponding to 1500 mg levocarnitine)
      • with a body weight up to 20 kg
        • Single dose: 1/2 or 1 bottle
        • Total dose: max. 4 x 1/2 bottles or 2 x 1 bottle, (corresponding to 2000 mg levocarnitine)
      • with a body weight up to 30 kg
        • Single dose: 1 bottle
        • Total dose: max. 3 x 1 bottle (corresponding to 3000 mg levocarnitine)
      • with a body weight over 30 kg
        • Single dose: 1 bottle
        • Total dose: 3 x 1 vials (corresponding to 3000 mg levocarnitine), but at most 5 bottles (corresponding to 5000 mg levocarnitine
  • There are no restrictions on the duration of taking the drug. If you take the preparation without a medical prescription and you are not sure about the duration of the intake, please ask your doctor or pharmacist.
  • Dosage in kidney dysfunction
    • In cases with severe restrictions on the primary urine volume (glomerulus filtrate below 10 ml/min), the intake should be taken under serum level control.
    • Dosage in blood laundry (hemodialysis)
      • After each blood washing, take 10 to 20 ml solution accordingly 1 - 2 g of levocarnitine, which are 1 to 2 vials after blood wash (hemodialysis).
    • Since it is a therapy to compensate for levocarnitine losses (substitution therapy) Depending on the clinical picture, your doctor, taking into account the above -mentioned laboratory controls, how long you should take the preparation.
  • Please speak to your doctor or pharmacist if you have the impression that the effect of the drug is too strong or too weak.

 

  • If you have taken a larger amount than you should
    • Even if the recommended dosage is exceeded temporarily, due to the extraordinarily low toxicity (toxicity) of levocarnitine, no poisoning (toxic effect) is expected. Special measures are then not required. If the therapy continued, please keep the recommended dosage.

 

  • If you have forgotten the intake
    • Do not take the double dose if you have forgotten the prior intake.

 

  • If you cancel the intake
    • You must immediately stop taking the drug when serious side effects occur or hypersensitivity (allergy). If you cancel the intake of the preparation for these or other reasons, apart from a success that may not be sufficient, no further undesirable consequences can be expected.

 

  • If you have any further questions about the application of the drug, ask your doctor or pharmacist.

Taking

  • Please take the solution undiluted.

Patient information

  • Particular caution when taking the drug is required,
    • if you suffer from severely restricted kidney function, you should not take high doses of the preparation over longer periods. The security and effectiveness of levocarnitine to take (oral dosage forms) has not yet been sufficiently examined in patients with restriction of kidney function (renal failure). If levocarnitin is taken in high doses for a long time, this can lead to the trimethylamin (tma) or trimethylamine n-oxide (TMAO), enriched in the blood instead of excreted with the urine. Therefore, please do not apply high doses of the drug over longer periods if you have a highly restricted kidney function or are regularly treated with blood washes as a result of severe kidney dysfunction or kidney failure.
      • The insufficient removal of TMA from the blood can also lead to the development of the so -called fish smell syndrome. This creates a fishing smell in breath, urine and sweat. In contrast, these undesirable side effects can largely be avoided in the event of intravenous administration of levocarnitine. The preparation is therefore also available as a injection solution for bloodwear patients with serious kidney dysfunction or kidney failure (dialysis patients with terminal renal failure).
      • Since levocarnitine is an body's own substance that is not dismantled by metabolic processes according to the present studies, but still excreted through the urine, depending on the degree of dysfunction, increases in the dose-dependent levocarnitine plasma mirror can occur. In the case of severe kidney dysfunction, please note the corresponding information on the dosage.
    • if you have a blood wash (chronic hemodialysis). The administration of levocarnitine can reduce triglyceride levels in patients under continuous treatment by blood laundry (chronic hemodialysis). Since an increase in the HDL cholesterol concentration was also observed in some cases, triglycerides and VLDL and HDL cholesterol should be monitored regularly. The dosage of lipid -reducing drugs (lipid skirts) must be adjusted accordingly.
    • if you are diabetic. In diabetics, the administration of levocarnitine improves the utilization of glucose (glucose). If you insulin or other blood sugar-lowering Aapplying RZNEIDEN, while taking levocarnitine at the same time, so -called hypoglycaemia (hypoglycaemia) can occur. For this reason, the blood sugar level must be checked regularly in such cases so that the dosage of blood sugar-reducing drugs can be corrected accordingly.

 

  • Wateriness and operating machines:
    • The medicine has no influence on the traffic or operating machines.

Pregnancy

  • Ask your doctor or pharmacist for advice before taking or using all drugs.

Hints

Read the package supplement and ask your doctor or pharmacist for risks and side effects.

Miscellaneous

- The urine can take a slightly fish -like smell (harmless).
- Certain blood fat values can fall (triglyceride levels) or rise (HDL cholesterol concentration) for blood linen. Therefore, the blood fat values should be checked regularly. The amount of lipid -reducing medicines must be adjusted accordingly

Manufacturer:  ALFASIGMA S.P.A., via Ragazzi del '99 n. 5, 40133 Bologna

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