KREON For children granulate, 20 g

Instructions for use for KREON For children granulate, 20 g

Detailed instructions for KREON For children granulate, 20 g

Field of use

• What is the drug?
  • It contains an enzyme mixture that is called "pancreatic powder.
  • Pancreas powder supports digestion. The enzymes are obtained from pancreas.
  • The small, gastric-resistant pellets slowly release the pancreas powder into the intestine. With this preparation for children, the pellets are particularly small.
  • The preparation is especially for children and toddlers who cannot swallow capsules. It is used when low doses are required pancreatic powder and particularly small pellets.
• The medicine is used at
  • Digestion disorders (maldigration) as a result of insufficient or missing function of the pancreas (exocrine pancreatic insufficiency).
  • Mukoviscidosis to support the insufficient function of the pancreas.
• How this medicine works
  • The enzymes in this preparation digest food on their way through the gastrointestinal tract. You should take the medicine during or immediately after a meal or snack. This allows the enzymes to mix thoroughly with food.
    

Active ingredients / ingredients / ingredients

60.12 mg pancreas powder (from pig)
5000 Pheur-E triacylglycerollipase
3600 Pheur-e Amylase
200 PHEUR-E Proteases
Cetyl alcohol auxiliary material (+)
Dimeticon 1000 Hedge Terms (+)
Hypromellical phthalate Hedge substance (+)
Macrogol 4000 auxiliary substances (+)
Triethyl citrat auxiliary substance (+)

Contradictions

• The medicine must not be taken
  • in the case of proven hypersensitivity to pork (pork energy) or one of the other components of this drug.

dosage

• Take or administer this medicine as described or exactly after the agreement made with your doctor or pharmacist. Ask your doctor or pharmacist if you are not sure.
• The dosage is measured in "lipase units". Lipase is one of the enzymes in the pancreatic powder. Various strengths of this drug contain different amounts of lipase.
• Always follow your doctor's instructions on how much you should take or administer.
• Your doctor determines the right dose for you. This is based on:
  • the severity of the disease
  • the weight
  • diet
  • the fat content in the chair
• If you or your child continue to have a fat stool or other stomach or intestinal complaints (gastrointestinal symptoms), speak to your doctor because the dosage may have to be adjusted.
• The amount prescribed by the doctor is measured with the measuring spoon attached to the pack. The gastric -resistant pellets correspond to 5000 lipase units (a measuring spoon).
• How much is to be taken
  • For patients with cystic fibrosis
    • Children:
      • Unless otherwise prescribed by the doctor, the usual dose for infants is a measuring spoon filling (100 mg) gastric -resistant granules (corresponding to 5000 lipase units) at any meal.
      • The usual initial dose for children under the age of 4 is 1000 lipase units per kilogram of body weight per meal.
      • The Üinitial initial dose for children from 4 years is 500 lipase units per kilogram of body weight per meal.
    • Young people and adults:
      • The weight-based enzyme dose should begin in adolescents and adults with 500 lipase units per kilogram of body weight per meal.
    • For all ages:
      • Your daily total dose should not exceed 2,500 lipase units per meal per kilogram per meal, or 10,000 lipase units per kilogram of body weight per day or 4,000 lipase units per gram of fat intake.
  • For patients with other pancreas
    • Young people and adults:
      • The usual dose for a meal is between 25,000 and 80,000 lipase units (corresponding to 5 to 16 measuring spoons). The usual dose for a snack is half of the dose for a meal.

• If you have taken or administered a larger amount than you should
  • If you have taken or administered a larger amount than you should, a lot of water should be drunk. Talk to your doctor or pharmacist. Very high doses of pancreatic powder sometimes caused an increase in uric acid in blood (hyperuricaemia) and urine (hyperuricosuria).

• If you have forgotten the intake/gift
  • Do not take or give twice the amount if you have forgotten the prior intake/gift.

• If you cancel the intake/administration
  • Do not break the intake or gave off without having spoken to your doctor beforehand. Many patients have to take this preparation for the rest of their lives.

• If you have any further questions about the application of this medicine, please contact your doctor or pharmacist.

Taking

• When is the preparation to be taken
  • Take or administer the preparation during or immediately after a meal or a snack. This allows the enzymes to mix thoroughly with the food and digest them while it goes through the intestine.
• How should the preparation be taken?
  • It should always be taken together with a meal or a snack.
  • Add the pellets to a small amount of a soft, acid food or acid liquid. Saure soft dishes can e.g. B. be yogurt or apple sauce.
  • Sour liquids can be apple, orange or pineapple juice. The mixture must be swallowed immediately without chopping or chewing it. A little water or juice should be added.
  • Alternatively, you can mix the pellets with a small amount of milk on a spoon and immediately give the child. Don't put the pellets in a baby bottle.
  • Mix in non-acid food or liquid, crush or chew the pellets can lead to irritation in the mouth or change the mode of action in the body.
  • Make sure that the medicine and the food mixture are completely swallowed and no pellets remain in the mouth.
  • Do not store the mixture.
  • There must be a sufficient supply of fluid.
  • The gastric -resistant pellets can also be administered by a PEG (percutaneous endoscopic gastrostomy) gastric tube. If your doctor has recommended to give you KREON for children via a PEG gastric tube, please contact this medicine exactly according to the consultation made with your doctor.
    

Patient information

• Warnings and special precautions
  • Please speak to your doctor or pharmacist before taking this medicine.
  • Particular caution when taking it is required,
    • if you or Your child of cystic fibrosis, a congenital metabolic disorder, suffering and therefore receiving pancreatic powder from the pig in high doses, there is the possibility in individual cases that intestinal narrowing (strictures) form in certain proportions of the thin and large intestine. These narrowing may lead to an intestinal obstruction. The following symptoms can be on an intestinal obstruction hindependent: nausea and vomiting, belching, bloating with stool and wind cover in connection with (violent) colic-like pain.
    • If strong and possibly unusual complaints occur in the area of the digestive tract with you or your child, a doctor must be consulted immediately.
    • if unusual gastrointestinal complaints or changes occur in the symptom. You should have this examined by your doctor as a precaution in order to rule out the possibility of damage to the intestine. This applies in particular to patients who take over EUR 10,000 per kg per kg of body weight every day.

• Wateriness and ability to operate machines
  • There are no effects on impairing the traffic and operating of machines.

Pregnancy

• There is no sufficient experience with the application of this drug in pregnant women. There are insufficient data from animal experimental studies in relation to pregnancy, development of the unborn child, childbirth and development of the child after birth. The possible risk for humans is not known. If you are pregnant or if you breastfeed, you should not take this medicine unless your doctor considers intake to take it is absolutely necessary.

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