ISOTONISCHE Saline solution Fresenius Freeflex, 50x100 ml

Instructions for use for ISOTONISCHE Saline solution Fresenius Freeflex, 50x100 ml

Field of use

• This medicine is a potassium -free 0.9%sodium chloride solution for infusion.
• It serves as a plasmaisotoner (in terms of quantity of approximately the same electrolyte content as in the blood plasma) fluid replacement when the body fluid is lost:
  • hypotone dehydration (water loss with an incidental increased salt loss)
  • isotone dehydration (water and salt loss in the same proportions).
• In addition, the drug serves as a short -term intravasal volume replacement (increase in liquid volume within the blood vessels), as a carrier solution for electrolyte concentrates and with the solution compatible (compatible) medication and for moistening associations.
• If you don't feel better or worse, contact your doctor.

Active ingredients / ingredients / ingredients

2.25 g sodium chloride
38.5 mmol sodium ion
38.5 mmol chloride ion
Sodium hydroxide auxiliary substance (+)
Salic acid, concentrated auxiliary material (+)
Water, for injection purposes auxiliary material (+)

Contradictions

• The medicine must not be used,
  • if you are hypersensitive (allergic) against sodium chloride or one of the other components of the drug
  • if you suffer from overgrading (hyperhydration states).

dosage

• Always apply this medicine exactly as described here.
• This drug (0.9%solution of sodium chloride) represents a so -called basic electrolyte solution, which, among other things,. To keep the veins open, as a carrier or solvent for medication and for isotone fluid intake.
• The recommended dose is:
  • The dosage is usually based on the fluid and electrolyte requirement (40 ml/kg body weight and day or approx. 6 mmol sodium/kg body weight and day).
  • The size of the sodium deficit can be estimated according to the following formula: na+ -deficit (mmol) = (Na+-Soll - Na+-St) x kg kg x 0.2 (the extracellular - not in the cells - volume of the body fluid is calculated from body weight in kilograms x 0.2).
• Maximum daily dose
  • The maximum daily dose is determined by the fluid and electrolyte requirement. A guideline of 3 - 6 mmol sodium/kg body weight/day applies to adults, a liquid intake of 40 ml/kg kg and day or approx. 6 mmol sodium per kg body weight and day should not be exceeded in adults.
• Maximum infusion speed
  • The maximum infusion speed depends on the clinical situation.
• Application in children and adolescents
  • Maximum daily amount:
    • The maximum daily dose is determined by the fluid and electrolyte requirement. A guideline of 3 - 5 mmol sodium /kg body weight /day applies to children.
• For the production of Parenteralia (injection or infusion preparations):
  • Dosage, duration of use and administration, intravenous injection/infusion (in the vein), intramuscular injection (in the muscle) or subcutaneous injection (under the skin), are based on the corresponding information for the diluted/dissolved medicine.

 

• If you have used a larger amount than you should
  • The following symptoms can occur in the event of an overdose:
    • Overgrading
    • excessed sodium or chloride blood level (Hydernatremia or hyperchloremia)
    • increased osmotic pressure in the blood (hyperosmolarity)
    • Creating a metabolic disorder with acidification of the blood (induction of an acidotic metabolism).
  • Therapy: In the event of an overdose as a result of an overdose of this drug, the liquid intake must be canceled and the administration of rapidly acting diuretic means (diuretics, e.g. furosemide). If an oligo anuria (severely restricted urine production) occurs, hemofiltration, hemodialysis or hemodiafiltration canug by a suitable kidney replacement procedure).

Taking

• This medicine is given via the (small) veins (intravenous application).
• For the production of Parenteralia (injection or infusion preparations):
  • To dissolve and dilute medicines immediately before use.
  • Dosage, duration of use and administration, intravenous injection/infusion (in the vein), intramuscular injection (in the muscle) or subcutaneous injection (under the skin), are based on the corresponding information for the diluted/dissolved medicine.

Patient information

• Warnings and Precautions
  • Special caution is required at
    • dilated potassium content in the blood (hypocalaemia)
    • increased sodium content in the blood (Hyprenatremia)
    • increased chloride content in the blood (hyperchloremia)
  • Caution is also required for diseases in which a reserved sodium intake is required, such as
    • Heart failure
    • Tissue swelling (generalized edema)
    • Liquid accumulation in the lungs (pulmonary edema)
    • High blood pressure
    • heavy functional disorders of the kidney (renal failure)
    • pregnancy disease states with high blood pressure, cramps and fluid accumulation in the tissue (eclampsia)
  • Depending on the volume supplied and the patient's condition, controls of the electrolyte and fluid status may be required.
  • If one of these points applies to you, your doctor may adapt the treatment or give you special information.
  • Children and adolescents
    • The medicine is suitable for adults and children.

 

• Wateriness and operating machines
  • The medicine has no influence on the ability to use and the ability to use machines.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant to be pregnant, you will ask your doctor or pharmacist for advice before using this drug.
• There are no concerns about an application during pregnancy and breastfeeding if the treatment event is appropriate.

Hints

Manufacturer:  Fresenius Kabi Deutschland GmbH, Else-Kröner-Straße 1, 61352 Bad Homburg v.d.H.