IBU-RATIOPHARM directly 200 mg powder to take, 20 pcs

Instructions for use for IBU-RATIOPHARM directly 200 mg powder to take, 20 pcs

Detailed instructions for IBU-RATIOPHARM directly 200 mg powder to take, 20 pcs

Field of use

Short -term symptomatic treatment of: light to moderately severe pain, fever. -Direkt 200 mg: Application in children from 20 kg body weight (from 6 years), adolescents and adults. -Direkt 400 mg: Application for young people from 40 kg body weight (from 12 years) and adults.

Mode of action

IBU Ratiopharm directly 200 mg powder to take is a pain reliever for direct intake without water.

Active ingredients / ingredients / ingredients

Pain reliever ibuprofen, isomalt (Ph.Eur.) (Containing Glucose and Sorbitol (Ph.EUR.)), Citronenic acid, acesulfam potassium, glycer alcohol (ph. Aroma extracts, maltodextrin, all-rac-α-tocopherol).

Contradictions

Hypersensitivity to the active ingredient or one of the other components, known reactions of bronchospasm, asthma, rhinitis, angioedema or urticaria.

dosage

In children and adolescents, the recommended dose is 7–10 mg/kg body weight as a single dose up to a maximum daily dose of 30 mg/kg body weight adults and adolescents (kg ≥ 40 kg, from 12 years): single dose 200–400 mg, Max. TD 1,200 mg ibuprofen.

Taking

• To take.
• The powder does not have to be taken together with liquid; The powder dissolves on the tongue and is swallowed with the saliva. This dosage form can be used in situations in which no liquids are available.
• In patients with sensitive stomach, it is recommended to take the medicine during meals.

Patient information

• Warnings and Precautions
  • Please speak to your doctor or pharmacist before taking this preparation:
    • in the case of a congenital blood formation disorder (e.g. acute intermittent porphyria)
    • for certain diseases of the immune system (systemic lupus erythematosus and mixed collagenosis)
    • for gastrointestinal diseases or chronic inflammatory intestinal diseases (ulcerative colitis, Crohn's disease)
    • with limited kidney or liver function
    • with drying out
    • for high blood pressure or heart failure (heart failure)
    • in allergies (e.g. skin reactions to other medicines, asthma, hay fever), nasal polyps, chronic swelling of the nasal mucosa or chronic, airways narrowing airways, since they then have an increased risk of the occurrence of a hypersensitivity reaction
    • if you recently undergone a larger operation.
  • Side effects can be reduced by using the lowest effective dose via the shortest period required for symptom control.
  • Security in the gastrointestinal tract
    • The simultaneous use of ibuprofen with NSAID, including selective cyclooxygenase-2 inhibitors, should be avoided.
  • Older patients:
    • In older patients, side effects occur more frequently after using NSAIDs, in particular bleeding and breakthroughs in the stomach and intestinal area, the UNThe can be fatal.
  • Bleeding of the gastrointestinal tract, ulcers and breakthroughs (perforations):
    • Bleeding of the gastrointestinal tract, ulcers and perforations, also with a fatal outcome, were reported during treatment with all NSAIDs. They occurred with or without prior warning symptoms or serious events in the gastrointestinal tract in the prehistory at any time of therapy.
    • The risk of the occurrence of gastrointestinal bleeding, ulcers and breakthroughs is higher with increasing NSAR dose, in patients with ulcers in the history, especially with the complications bleeding or breakthrough, and in older patients. You should start treatment with the lowest available dose. Please speak to your doctor because combination therapy with protective medicinal products (e.g. misoprostol or proton pump inhibitor) could be considered. This also applies if you also take low-dose acetylsalicylic acid (Aspirin) or other active ingredients that can increase the risk of gastrointestinal diseases.
    • If you have a history of side effects on the gastrointestinal tract, especially at older age, you should report any unusual symptoms in the abdomen (especially gastrointestinal bleeding), especially at the beginning of the therapy. Caution is advisable if you get medicines that can increase the risk of ulcers or bleeding, such as: B. Oral corticosteroids, anti-blood clotting medicines such as warfarin, selective serotonin reuptake inhibitors or platelet aggregation inhibitors such as acetylsalicylic acid.
    • If there is gastrointestinal bleeding or ulcers during treatment with ibuprofen, the treatment is to be stopped and a doctor is consulted.
    • If you have a gastrointestinal disease (ulcerative colitis, Crohn's disease) or in the past, you should use NSAR with caution because your condition can deteriorate.
  • Effects on the cardiovascular system and on the brain vessels
    • Anti -inflammatory agents/painkillers such as ibuprofen can go hand in hand with a slightly increased risk of heart attack or stroke, especially when using in high doses.
    • Do not exceed the recommended dose or duration of treatment.
    • You should discuss your treatment with your doctor or pharmacist before taking this medicine
      • having heart disease, including heart failure (heart failure) and angina (chest pain), or a heart attack, a bypass operation, peripheral arterial disease (circulatory disorders in the legs or feet due to the narrowed or closed arteries) or any kind of stroke (including mini Had stroke or transitory ischemic attack, "tia").
      • Heavy prints, diabetes or high cholesterol levels or heart diseases or strokes occur in their family history or when they are smokers.
  • Skin reactions
    • Under NSAR therapy, serious skin reactions with redness and bladder formation, some with a fatal outcome, were reported (exfediative dermatitis, Stevens-Johnson syndrome and toxic epidermal necrolysis/lyell syndrome). The highest risk of such reactions seems to exist at the beginning of therapy, since these reactions occurred in the majority of cases in the first month of treatment. At the first sign of rashes, mucosal defects or other signs of a hypersensitivity reaction, ibuprofen should be discontinued and the doctor should be consulted immediately.
    • Use of ibuprofen should be avoided during a chickenpox infection (varicella infection).
  • Effects on the kidneys:
    • Ibuprofen influences the blood flow to the kidneys (kidney perfusion), which can also hold back (retention) of sodium, potassium and liquid in patients who have not previously suffered from kidney diseases. This can lead to fluid deposits (edema) or even heart failure or high blood pressure in susceptible patients. There are reports on acute kidney inflammation (interstitial nephritis) and damage to the kidneys. The highest risk is in patients with nierdisorders, heart failure or liver dysfunction, when taking drainage agents (diuretics) or so-called ACE inhibitors as well as in older patients. After stopping the NSAID therapy, the condition is generally restored before the start of treatment.
  • Allergic reaction
    • Severe acute hypersensitivity reactions (e.g. anaphylactic shock) are very rarely observed. At the first sign of a hypersensitivity reaction after taking/using ibuprofen, the therapy must be canceled. The symptoms corresponding, medically required measures must be initiated by expert persons.
  • Other Information
    • Ibuprofen, the active ingredient of this drug, can temporarily inhibit the platelet function (thrombocyte aggregation). Patients with blood clotting disorders should therefore be carefully monitored.
    • If Ibuprofen is permanently involved, regular control of the liver values, kidney function and the blood count is required.
    • When taking this drug before surgical interventions, the doctor or dentist must be asked or informed.
    • You should drink enough during therapy, especially if fever, diarrhea or vomiting appear.
    • NSAIDs like ibuprofen can disguise the symptoms of infections and fever.
    • By using NSAID in combination with alcohol, the active ingredient side effects, in particular those that affect the gastrointestinal tract or the central nervous system, can be reinforced.
    • The longer use of all kinds of painkillers against headaches can make them worse. If this is the case or if this is suspected, medical advice should be obtained and treatment can be broken off. The diagnosis of headache in the case of pharmaceutical use (Medication Overuse Headache, MOH) should be suspected in patients who suffer from frequent or daily headaches, although (or precisely because) they regularly take medicines for headaches.
    • In general, the habitual intake of pain relievers, especially when combining several pain relieving active ingredients, can lead to permanent kidney damage with the risk of kidney failure (analgesic nephropathy).
• Children and adolescents
  • Ibuprofen must not be used in children below 20 kg body weight or under 6 years, since this dose strength is not suitable due to the higher active ingredient content.
  • There is a risk of kidney dysfunction in dehydrated children and adolescents.

 

• Wateriness and ability to operate machines
  • Since side effects such as fatigue, dizziness and visual disturbances can occur when using ibuprofen, the reaction capacity can be changed in individual cases and the ability to actively participate in road traffic and to operate machines can be impaired. This applies even more in combination with alcohol.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before taking this drug.
• Pregnancy
  • If pregnancy is determined during the application of ibuprofen, the doctor must be notified. In the first 6 pregnancy months, you can only use ibuprofen after consultation with your doctor. In the last 3 months of pregnancy, ibuprofen may not be used due to an increased risk of complications for mother and child.
• Breastfeeding
  • The active ingredient ibuprofen and its dismantling products only pass into breast milk in small quantities.
  • Since adverse consequences for the infant have not yet become known, with short -term use in the recommended dose for treatment, an interruption of breastfeeding will generally not be necessary.
• Reproductive ability
  • The medicine belongs to a group of medicines (non-steroidal anti-rheumatics, nsar) that can affect the fertility of women. This effect is reversible after stopping the drug (reversible).

Hints

Do not apply longer for pain or fever without medical advice than specified in the package insert!

Manufacturer:  ratiopharm GmbH, Graf-Arco-Straße 3, 89079 Ulm